Search on: PERIVENTRICULAR LEUKOMALACIA 
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Descriptor English:   Leukomalacia, Periventricular 
Descriptor Spanish:   Leucomalacia Periventricular 
Descriptor Portuguese:   Leucomalácia Periventricular 
Synonyms English:   Encephalomalacia, Periventricular
Periventricular Leukomalacia
Cystic Periventricular Leukomalacia
Neonatal Cerebral Leukomalacia  
Tree Number:   C10.228.140.300.700
C10.228.140.461.550
C14.907.253.612
C16.614.521.450
Definition English:   Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1) 
Indexing Annotation English:   periventricular refers to the cerebral ventricles
History Note English:   1991(1987) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RA radiography RI radionuclide imaging
RT radiotherapy RH rehabilitation
SU surgery TH therapy
US ultrasonography UR urine
VE veterinary VI virology
Record Number:   19229 
Unique Identifier:   D007969 

Occurrence in VHL: 		 

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